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Repetitive Transcranial Magnetic Stimulation (rTMS) in Obsessive Compulsive Disorder
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Adel
M. Elmedany1, Walid F. Ismail1, Hanan H. Elgendy2,
Mohamed Galal Sheleel3
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Departments of
Neurology, Al-Azhar University1; Cairo University2;
Neuropsychiatry3,
Dar El Shefa Hospital; Egypt
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ABSTRACT
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Background: obsessive-compulsive disorder is one of anxiety disorders, which
characterized by obsessive thoughts in addition to the compulsive acts to
reduce tension. Objective: This study was done to examine the effectiveness
of repetitive transcranial magnetic stimulation (rTMS) in the treatment of
obsessive-compulsive Egyptian patients, and to test its efficacy alone or
combined with drug therapy. Methods: The study included 20
obsessive-compulsive patients (9 males and 11 females). The patients are
divided into two groups: group (A) newly diagnosed patients not on treatment
and group (B) patients old diagnosed patients on treatment. DSM-IV-TR 2000 and
Yale-Brown Scales were used as diagnostic materials. In addition, apply
repetitive transcranial stimulation (r-TMS) to the left prefrontal area of the brain in eight sections. Results:
There is no statistically significant difference between age and severity of
the disease. There is no statistical significant difference between both groups
regarding marital status and family history. There is stastically significant
difference between responses of the patients of both groups after rTMS
(P<0.05). In addition, group (B) response is better. Conclusion:
Patients of Obsessive-compulsive
disorder after repetitive
transcranial magnetic stimulation has a better response especially those accompanied
with pharmacological treatment. [Egypt
J Neurol Psychiat Neurosurg. 2014; 51(3): 369-373]
Key words: obsessive-compulsive disorder, TMS
Correspondence to M. Galal Sheleel, Department of
Neuropsychiatry, Dar El Shefa Hospital. Tel.:
+201111999624 Email: m.sheleel@gmail.com
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