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July2014 Vol.51 Issue:        3       (Supp.) Table of Contents
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Repetitive Transcranial Magnetic Stimulation (rTMS) in Obsessive Compulsive Disorder

Adel M. Elmedany1, Walid F. Ismail1, Hanan H. Elgendy2, Mohamed Galal Sheleel3

Departments of Neurology, Al-Azhar University1; Cairo University2;

Neuropsychiatry3, Dar El Shefa Hospital; Egypt


Background: obsessive-compulsive disorder is one of anxiety disorders, which characterized by obsessive thoughts in addition to the compulsive acts to reduce tension. Objective: This study was done to examine the effectiveness of repetitive transcranial magnetic stimulation (rTMS) in the treatment of obsessive-compulsive Egyptian patients, and to test its efficacy alone or combined with drug therapy. Methods: The study included 20 obsessive-compulsive patients (9 males and 11 females). The patients are divided into two groups: group (A) newly diagnosed patients not on treatment and group (B) patients old diagnosed patients on treatment. DSM-IV-TR 2000 and Yale-Brown Scales were used as diagnostic materials. In addition, apply repetitive transcranial stimulation (r-TMS) to the left prefrontal area of the brain in eight sections. Results: There is no statistically significant difference between age and severity of the disease. There is no statistical significant difference between both groups regarding marital status and family history. There is stastically significant difference between responses of the patients of both groups after rTMS (P<0.05). In addition, group (B) response is better. Conclusion: Patients of Obsessive-compulsive disorder after repetitive transcranial magnetic stimulation has a better response especially those accompanied with pharmacological treatment. [Egypt J Neurol Psychiat Neurosurg.  2014; 51(3): 369-373]

Key words: obsessive-compulsive disorder, TMS

Correspondence to M. Galal Sheleel, Department of Neuropsychiatry, Dar El Shefa Hospital. Tel.: +201111999624    Email:

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