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Effect of Prophylactic Treatment on Visual Evoked Potentials (P100) in Migraineurs
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Mamdouh
Ali Kotb1, Sayed Sobhy2, Nermine Ali Hamdi1
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Department of
Neurology, Elminia University1; Fayoum University2; Egypt
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ABSTRACT
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Background: Migraine is a common neurovascular disorder. Visual evoked potential
(VEP) changes, between migraineurs and normal subjects, were often conflicting.
Objective: Compare VEP (P100) in patients with migraine with and without
aura to normal subjects, and the effect of prophylactic treatment. Methods:
Visual evoked potential was recorded in 32 patients with migraine and 15 healthy
control subjects. Results: P100 amplitude was significantly higher and
its latency was significantly longer in patients with migraine compared to
control subjects, this difference disappeared in patients with regular
prophylactic treatment. Conclusion: Cortical excitability changes may be
related to the pathophysiology of migraine and the efficacy of prophylactic
treatment. [Egypt
J Neurol Psychiat Neurosurg. 2014; 51(3) : 321-326]
Key words: Visual
evoked potential, P100, migraine.
Correspondence to Sayed Sobhy,2 Department of
Neurology, Fayoum University, Fayoum. Egypt. Tel.: +01222190502. Email: sobhysayed@hotmail.com
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