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Cognitive Aspects of Benign Focal Epilepsy of Childhood: A Neurophysiological and Neuropsychological Study
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Nihal Z. El Shazly1, Gihan M. Ramzy2, Mye
A.Basheer1, Mohamed A .El Sayed2
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Departments
of Clinical Neurophysiology1, Neurology2, Faculty of
Medicine, Cairo University; Egypt
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ABSTRACT
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Background: Subtle cognitive deficits and
defective school performance were previously reported in school children with
Benign Focal Epilepsy (BFE). Objective: To assess possible alterations
in cognitive and psychological functions in school children having BFE in
comparison to age and sex matched healthy children. Methods:
Neurophysiological assessment using EEG, P300 and Contingent Negative Variation
and Neuropsychological assessment using Wechsler Intelligence Scale for
Children were carried out on 30 school children
(age 5-11 years ) suffering from Benign Focal Epilepsy as well as 30 age
and sex matched healthy children. Results: Patient group had
significantly lower P300 amplitudes (p= 0.02), and tendency to higher mean CNV.
Patients who had right side EEG spikes
had significantly lower scores in the Total IQ, and Total Verbal IQ however
patients who had left side spikes had significantly lower P300 amplitude (p=
0.04) and higher mean Contingent Negative Variation . Conclusion: Benign
Focal Epilepsy is a probable cause of cognitive deficits and educational
problems among school children. [Egypt
J Neurol Psychiat Neurosurg. 2014; 51(2): 243-248]
Key Words: Benign focal epilepsy, psychometric assessment, event related
potentials, contingent negative variation.
Correspondence to Nihal
Z. El Shazly, Department of Neurophysiology, Faculty of Medicine, Cairo
University, Egypt. Email: Nihalelshazly@yahoo.com
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