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October2013 Vol.50 Issue:        4        Table of Contents
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Transcranial Duplex Measurements Correlate Positively with Cerebral Blood Flow and Clinical Outcome in Post Stroke Aphasia

Nirmeen A. Kishk, Reham M. Shamloul, Asmaa M. Ebraheim

Department of Neurology, Cairo University; Egypt


Background: The recovery of speech in patients with ischemic stroke in dominant hemisphere depends on compensatory reserves of cerebral hemodynamics and collateral brain circulation. Trans-cranial duplex (TCD) is a useful noninvasive method for assessment of intracranial circulation and its value as a prognostic indicator has been a subject of great interest. Objective: Toexamine the prediction of language recovery based on intracranial circulation assessment using TCD indices in individuals with post-stroke aphasia. Methods: Twenty five right handed patients with post ischemic stroke aphasia were included in this study. CT brain imaging was carried out for all patients to document ischemic etiology. During the acute stage and after 3 month during the recovery period, aphasia was evaluated using Kasr al-Aini Aphasia Test (KAAT) and the patients were assessed using extra- and trans-cranial duplex ultrasonography to evaluate extra- and intra-cranial vasculature. Results: In the present study, Broca‚Äôs aphasia was the most frequent aphasic syndrome in the acute stage of ischemic stroke in the territory of the middle cerebral artery (MCA). Aphasia improvement percent shows significant positive correlation with MCA peak systolic velocity (PSV) on both sides measured initially and after 3 months. Cerebral blood flow volume (CBFV) improvement percent correlated positively with follow up Lt anterior cerebral artery (ACA) peak systolic velocity and negatively with follow up RtACA (PSV). Conclusion: TCD is a non-invasive diagnostic and prognostic indicator that could be used as a bed side tool for immediate and follow up evaluation of the intracranial cerebral vasculaturein post-stroke aphasia in order to assess the recovery. [Egypt J Neurol Psychiat Neurosurg.  2013; 50(4): 449-454]

Key Words: Trans-cranial duplex, post-stroke aphasia

Correspondence to Nirmeen A. Kishk, Department of Neurology, Cairo University, Egypt. e-mail:


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