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October2013 Vol.50 Issue:        4        Table of Contents
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Relationship between Common Carotid Artery Intima Media Thickness and Post-Stroke Cognitive Impairment

Sami El-Shazli, KaramSelim, Tarek Goda

Department of Neurology, Zagazig University; Egypt


Background: Common carotid artery intima-media thickness (CCA-IMT) has been associated with different cerebrovascular diseases, but its association with vascular cognitive impairment has not been clarified. Objective: The purpose of this study was to investigate whether CCA-IMT is associated with cognitive impairment 6 months after an acute ischemic stroke. Methods: A total of 50 patients (32 males, 18 females) with a mean age 46.48±12.46, prospectively collected from neurology critical care unit in Zagazig university hospitals, with the first ever ischemic stroke, underwent brain imaging and carotid ultrasonography during hospitalization. Patients’ cognitive performance was assessed using the Mini-Mental State Examination (MMSE) during hospitalization and six months later. Results: CCA-IMT was significantly associated with cognitive impairment. Older age, hypertension, were also independently associated with post-stroke cognitive impairment. Conclusion: CCA-IMT was independently associated with cognitive impairment 6 months after an acute ischemic stroke. It might help in screening of stroke patients at risk of cognitive impairment. [Egypt J Neurol Psychiat Neurosurg.  2013; 50(4): 431-435]

Key Words: carotid intima media thickness, stroke, cognitive impairment.

Correspondence to Tarek Gouda, Neurology Department, Zagazig University; Egypt Tel.: +201115606539    e-mail:

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