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April2011 Vol.48 Issue:        2        Table of Contents
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Voiding Dysfunction in Parkinson's Disease

Rasha H. Soliman1, Amr Masoud2


Departments of Neurology1, Urology2, Beni Suef University; Egypt



Background: Voiding dysfunction and bladder disturbance often occur in patients with Parkinson's disease (PD) and severely disturb the quality of the patients' life. Objective: To evaluate the lower urinary tract dysfunction in PD patients and to study its possible association with various indices of the disease. Methods: Twenty-five PD patients (14 males, 11 females) were included and subjected to thorough neurological examination, clinical evaluation by Hoehn and Yahr staging and Unified Parkinson Disease Rating Scale (UPDRS). Lower urinary tract symptoms were evaluated by the international prostate symptom score (IPSS). Urodynamic study was done to all patients. Results: Urinary manifestations included irritative symptoms in 13 patients (52%), obstructive symptoms in 4 patient (16%) and total symptoms in 4 patients (16%). Urodynamic study was abnormal in 18 patients (72%), it included: detrusor hyper-reflexia in 14 patients (56%), prolonged time of micturition in 11 patients (44%), decreased maximum bladder capacity in 6 patients (24%), decreased maximum flow rate in 10 patients (40%), and presence of residual urine in 5 patients (20%). Only severity of the disease and quality of life index of IPSS were significantly associated with the urinary dysfunction, with no significant association between age, sex, duration of the disease or UPDRS scores and urinary dysfunction. Conclusion: Voiding dysfunction in PD patients is frequent, and progressively develops in advanced stages, affecting their quality of life, which has to be investigated early for proper evaluation, diagnosis and management. [Egypt J Neurol Psychiat Neurosurg.  2011; 48(2): 117-122]


Key Words: Parkinson's disease, urinary manifestations, urodynamic study




Correspondence to Rasha Hassan Soliman, Department of Neurology, Beni-Sueif University, Egypt.

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