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July2005 Vol.42 Issue:        2        Table of Contents
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The Evaluation of Cerebral Oxygenation in Ischaemic Stroke Patients

Salma Hamed Khalil

Department of Neurology, Ain Shams University


Background: The technology of transcranial near infrared spectroscopy (NIRS) for the measurement of cerebral oxygen balance was introduced 25 years ago. Until very recently there has been only occasional interest in its use during surgical monitoring. Now numerical clinical studies have at least partly succeeded in overcoming the long standing misunderstanding in reading its value. Aim: Our aim is to evaluate the clinical significance of estimation of the regional cerebral oxygen saturation (rSO2) in patients with ischaemic stroke by the cerebral oximetery during the acute phase. Thirty four patients were included in the current study with ischaemic stroke in the middle cerebral artery territory. Detailed clinical examination and appropriate lab investigations were done. The rSO2 was determined by the Somanting INVOS 3100 near infrared spectroscopy (NIRS) within two weeks of admission. The blood gases values were noted too. The changes were evaluated along with Glasgow Coma Scale (GCS), and the patients were classified according to their outcome to reversible group (recovered) and to irreversible group of patients (died). Results: evaluation of all patients showed that the values of cerebral oxygenation positively correlated with the GCS, although insignificantly. The rSO2 values were significantly higher in the reversible group of patients than in the irreversible group, after both the first and second weeks. The results of peripheral oxygenation did not correlate significantly either with the patients' outcome or with the cerebral oxygenation values. Conclusion: the cerebral oximetery can be used as a measure to evaluate the cerebral oxygenation during the acute phase of ischemic stroke, serving as a potentially useful marker for detection of cerebral oxygenation to judge the effectiveness of management and for the follow-up of patients with ischaemic stroke.

(Egypt J. Neurol. Psychiat. Neurosurg., 2005, 42(2): 485-492).


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