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July2007 Vol.44 Issue:        2        Table of Contents
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Cognitive Dysfunctions and Neuroimaging Findings in Patients with Chronic Cardiovascular Diseases (UAE Sample)

Abd El-Mohsen Y.1, Fakhry H.1, Abou Hagar A.2, Salah M.3, Abou El-Abbas H.4, El Nabawy H.A.5

Departments of Psychiatry, Cairo University1; Neuropsychiatry, Suez Canal University2; Internal Medicine, Qassimi Hospital3; Diagnostic Radiology, Theodor Bilharz Research Institute4, Al Rahba Hospital5



Executive skills mainly presented by memory may be sensitive to chronic systemic illness. Objectives: The present study is designed to assess prevalence of cognitive problems in patients with chronic cardio-vascular diseases. A trial is made to explore whether cognitive dysfunctions are age related or, due to the effects of superimposed present chronic cardiovascular disease. Methods: 60 patients with chronic cardio-vascular diseases subdivided into two groups composed of 30 elderly cardiovascular  patients (≥65y) and another 30 cardiovascular patients of younger age group 40-60y  were selected. Two control groups of 30 healthy individuals were selected as 15 elder ≥65y and 15 of younger age 40-60y. All groups were subjected to clinical medical and laboratory examination helping physical diagnosis. Psychological assessment by HAMD-17, NPI, MMSE, MTS and CDT were also performed to exclude depression and assess cognitive functions. Patients having cognitive impairment were further evaluated using Hachinski Ischemic Score to classify dementia type. Brain Computed Tomography (CT) was done for all patients groups.  Results: The prevalence of cognitive impairment was higher in elderly with chronic cardio-vascular illness than in elderly without illness (P<0.05). Only MTS showed  statistically significant decline in the younger group of patients than the young control group. Also there were statistically significant decline in the psychological tests scores of the elder than the younger group of patients (P<0.05). Dementia of Vascular type had the highest frequency among elder patient group  (56.7%) compared to (13.3%) in the younger group. Brain CT scan results were useful in the classification of cognitive dysfunction subtypes. Conclusion: Chronic cardio-vascular diseases may increase the possibility of cognitive impairment in old  people, however aging process may have a more important influence on cognitive impairment in the elderly.

(Egypt J. Neurol. Psychiat. Neurosurg., 2007, 44(2): 545-559)


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